Study on hypoglycemic effect of puer tea extract and green tea extract


Li Zhiwen, Wang Yuanyuan, Wang Gendai, Chen Yanfang, Li Changwen and Ma Xiaohui from the research institute of Tianshili Holding Group compared the hypoglycemic effect of Pu'er tea extract and green tea extract through the whole animal model study. C57BL/6J mice were used as the control group, and KKay mice were randomly divided into groups. Pu'er tea extract and green tea extract were given by gavage respectively for 4 weeks. Fasting blood glucose and area under the blood glucose curve were used as the observation indicators to compare their pharmacodynamic effects; The diabetic rats were made by intraperitoneal injection of streptozotocin (STZ) in SD male rats. The diabetic rats were randomly divided according to the initial fasting blood glucose value. Pu'er tea extract and green tea extract were given by gavage continuously for 4 weeks. The fasting blood glucose, area under the blood glucose curve and fasting serum insulin were used as observation indicators.

Li Zhiwen, Wang Yuanyuan, Wang Gendai, Chen Yanfang, Li Changwen and Ma Xiaohui from the research institute of Tianshili Holding Group compared the hypoglycemic effect of Pu'er tea extract and green tea extract through the whole animal model study. C57BL/6J mice were used as the control group, and KKay mice were randomly divided into groups. Pu'er tea extract and green tea extract were given by gavage respectively for 4 weeks. Fasting blood glucose and area under the blood glucose curve were used as the observation indicators to compare their pharmacodynamic effects; The diabetic rats were made by intraperitoneal injection of streptozotocin (STZ) in SD male rats. The diabetic rats were randomly divided according to the initial fasting blood glucose value. Pu'er tea extract and green tea extract were given by gavage continuously for 4 weeks. The fasting blood glucose, area under the blood glucose curve and fasting serum insulin were used as observation indicators.
The results showed that both Pu'er tea extract and green tea extract could reduce the fasting blood glucose of KKAY mice and STZ diabetic model rats, and both could reduce the area under the blood glucose curve, but the difference was that Pu'er tea extract was better than green tea extract in reducing the fasting blood glucose and the area under the blood glucose curve, and Pu'er tea extract could significantly reduce the fasting serum insulin of rats compared with the model group, However, there was no significant difference between the green tea extract and the model group in reducing fasting serum insulin. The inhibitory effects of two tea extracts on glycoaldehyde reductase and PTP1B, the target enzymes of diabetes in vitro, were compared. It was found that Pu'er tea extract had a strong inhibitory effect on PTP1B activity, with an inhibitory rate of 88.0%, while green tea extract had no inhibitory effect on this enzyme.
The comprehensive experimental results showed that the hypoglycemic effect of Pu'er tea extract was better than that of green tea extract.


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It has a clean area of more than 400 square meters, perfect pilot plant equipment and crystallization and purification equipment for high-content products. It can process more than 1000 tons of Chinese herbal medicine raw materials every year.

Hunan World Well-Being Biotech is an enterprise engaged in the research, development, production, processing and sales of natural plant extracts. The company has complete equipment for extraction, concentration, extraction, column chromatography, spray drying, vacuum drying, crushing, mixing, screening, packaging, HPLC, UV and so on. It has a clean area of more than 400 square meters, perfect pilot plant equipment and crystallization and purification equipment for high-content products. It can process more than 1000 tons of Chinese herbal medicine raw materials every year. convenient transportation. We made full use of the local natural drug resources in Shimen, Hunan Province, and developed Eucommia ulmoides extract (chlorogenic acid 5%-98%, 5% Eucommia ulmoides, 98% aucubin, 90% terpineol diglucoside, 90% Eucommia ulmoides glycoside), citrus extract (Citrus Fruit instant powder, 90% hesperidin, 30% synephrine, 96% dihydrochalcone, orange peel oil, etc.) Tea extracts (98% tea polyphenols, 80% catechin, 99% theanine, 99.9% theaflavin, 98% EGCG) and other standard plant extracts and various single traditional Chinese medicine extracts. The company provides plant extracts for processing, which are produced in full accordance with the customer's production process requirements, and strictly keep the customer's information confidential.

2022-10-13

The company provides plant extracts for processing, which are produced in full accordance with the customer's production process requirements, and strictly keep the customer's information confidential.

Based at home and facing the world, the company takes innovation as the core of the enterprise in concept, mechanism, management, marketing, technology, products and other aspects, implements near -, medium - and long-term planning oriented management, ensures the long-term, sustainable and leap forward development of the company, comprehensively improves the comprehensive quality of the enterprise, and forms its own intellectual property rights as the core technology, core products and management mode unique to scientific and technological small and medium-sized enterprises, To adapt to the development trend of global economic integration. The company takes into account the interests of shareholders, employees, society and other aspects, seeks the harmonious unity of the enterprise, nature and society, and makes more contributions to the country and society.

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It has rich production experience and strict quality control system, and has established a perfect sales service system

Our company is an enterprise specializing in the production and sale of natural green extracts, pharmaceutical intermediates, food and health food, cosmetics, food additives, feed additives as raw materials. The company has a number of scientific research, management and technical backbones, and has established close technical cooperation relations with colleges and universities and research institutions at home and abroad, and has hired domestic and foreign biotechnology experts as R & D consultants all the year round, as a strong backing for the company's R & D and technological upgrading. Relying on the independent cultivation and introduction of high-tech talents at home and abroad, and close cooperation with many scientific research institutions, a multidisciplinary, all-round and high-level technical and management elite team has been formed in the fields of extraction and separation, synthesis, fermentation, pharmacy, functional food chemistry, nutrition, biology, engineering, management and molecular structure modification. The company has complete extraction, separation, synthesis, physical sterilization and other production equipment, rich production experience and strict quality control system, and has established a perfect sales service system, with import and export rights and self-care inspection qualification.

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